![C43H55N4O10P uridine, 5 ′ -O- [bis (4-methoxyphenyl) phenylmethyl] -2 ′ -O- (2-methox yehyl)-5-methyl-, 3 ′-[2-cyanoethyl n, n-bis (1-methylethyl) phosphor amidite] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C43H55N4O10P uridine, 5 ′ -O- [bis (4-methoxyphenyl) phenylmethyl] -2 ′ -O- (2-methox yethyl)-5-methyl-, 3 ′-[2-cyanoethyl n, n-bis (1-methylethyl) phosphor amidite] (aci) na itinampok na imahe (1-methylethyl) na amidite] (ACI) na itinampok na imahe (1-methylethyl) amidite amidite] (aci)](https://cdn.globalso.com/nvchem/C43H55N4O10P-Uridine.png)
C43H55N4O10P uridine, 5 ′ -O- [bis (4-methoxyphenyl) phenylmethyl] -2 ′ -O- (2-methox yehyl)-5-methyl-, 3 ′-[2-cyanoethyl n, n-bis (1-methylethyl) phosphor amidite] (ACI)
Numero ng rehistro ng CAS
163878-63-5
H302
| Mga pangunahing katangian ng pisikal | Halaga | Kundisyon |
| Molekular na timbang | 818.89 | - |
| pka (hinulaang) | 9.55 ± 0.10 | Karamihan sa acidic temp: 25 ° C. |
Canonical smiles
N#CCCOP (OC1C (OC (N2C = C (C (= O) NC2 = O) C) C1OCCOC) COC (C = 3C = CC = CC3) (C4 = CC = C (OC) C = C4) C5 = CC = C (OC) C = C5) N (C (C) C) C (C) C.
Ngumiti si Isomeric
C (oc [c @@ h] 1 [c @@ h] (op (n (c (c) c) c (c) c) occc#n) [c @@ h] (occoc) [c @@ h] (o1) n2c (= o) nc (= o) c (c) = c2) (c3 = cc = c (oc) c = c3) (c4 = cc = C (OC) C = C4) C5 = CC = CC = C5
Inchi
Inchi = 1S/C43H55N4O10P/C1-29 (2) 47 (30 (3) 4) 58 (55-24-12-23-44) 57-38-37 (56-41 (39 (38) 53-26-25-50-6) 46-27-31 (5) 40 (48) 45-42 (46) 49) 2 8-54-43 (32-13-10-9-11-14-32,33-15-19-35 (51-7) 20-16-33) 34-17-21-36 (52-8) 22-18-34/H9-11,13-22,27,29-30,37-39,41H, 12,24-26,28H2, 1-8H3, (H, 45,48,49)/T37-, 38-, 39-, 41-, 58?/M1/S1
Inchi key
Yfrrkzdudxhjnc-Kzqaakllsa-n
17 iba pang mga pangalan para sa sangkap na ito
Uridine, 5 ′ -O-[bis (4-methoxyphenyl) phenylmethyl] -2 ′-O-(2-methoxyethyl)-5-methyl-, 3 ′-[2-cyanoethyl bis (1-methylethyl) posporo
amidite] (9ci); 10: PN: US20030212017 Pahina: 18 Inangkin ang RNA; 11: PN: US20030211606 Pahina: 18 Inangkin ang RNA; 13: PN: US20040
005569 Pahina: 21 Inangkin ang RNA; 13: PN: US20040006030 Pahina: 22 inaangkin ang RNA; 13: PN: US20040014048 Pahina: 19 inaangkin ang RNA; 13: PN: US20040014049 Pahina: 19 inaangkin ang RNA; 14: PN: US20030198965 Pahina: 19 inaangkin ang RNA; 14: PN: US20040005565 Pahina: 17- 22 inaangkin ang RNA; 14: PN: US20040005570 Pahina: 19 inaangkin ang RNA; 14: PN: US20040014047 Pahina: 19 inaangkin ang RNA; 14: PN: US20040
014699 Pahina: 19 inaangkin ang RNA; 15: PN: US20040014050 Pahina: 19 inaangkin ang RNA; 15: PN: US20040014051 Pahina: 21 inaangkin ang RNA; 15:
PN: WO03106645 Pahina: 69 Inangkin ang RNA; 16: PN: US20040006029 Pahina: 22 inaangkin ang RNA; 87: PN: US20040005707 Pahina: 19 inaangkin ang RNA
Magagamit ang spectra
1 h nmr
13 C NMR
Hetero nmr
Magagamit ang mga pag -aari
Biological
Kemikal
Lipinski
May kaugnayan sa istraktura
| Ari -arian | Halaga | Kundisyon | Pinagmulan |
| Bioconcentration factor | 348 | pH 1; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 2810 | Ph 2; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 21100 | Ph 3; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 63100 | Ph 4; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 78800 | Ph 5; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 80800 | Ph 6; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 80800 | Ph 7; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 78800 | Ph 8; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 63400 | Ph 9; Temp: 25 ° C. | (1) ACD |
| Bioconcentration factor | 21800 | Ph 10; Temp: 25 ° C. | (1) ACD |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
| Ari -arian | Halaga | Kundisyon | Pinagmulan |
| KOC | 487 | pH 1; Temp: 25 ° C. | (1) ACD |
| KOC | 3940 | Ph 2; Temp: 25 ° C. | (1) ACD |
| KOC | 29600 | Ph 3; Temp: 25 ° C. | (1) ACD |
| KOC | 88400 | Ph 4; Temp: 25 ° C. | (1) ACD |
| Ari -arian | Halaga | Kundisyon | Pinagmulan |
| KOC | 1.10 x 105 | Ph 5; Temp: 25 ° C. | (1) ACD |
| KOC | 1.13 x 105 | Ph 6; Temp: 25 ° C. | (1) ACD |
| KOC | 1.13 x 105 | Ph 7; Temp: 25 ° C. | (1) ACD |
| KOC | 1.10 x 105 | Ph 8; Temp: 25 ° C. | (1) ACD |
| KOC | 88800 | Ph 9; Temp: 25 ° C. | (1) ACD |
| KOC | 30600 | Ph 10; Temp: 25 ° C. | (1) ACD |
| logd | 4.39 | pH 1; Temp: 25 ° C. | (1) ACD |
| logd | 5.30 | Ph 2; Temp: 25 ° C. | (1) ACD |
| logd | 6.18 | Ph 3; Temp: 25 ° C. | (1) ACD |
| logd | 6.65 | Ph 4; Temp: 25 ° C. | (1) ACD |
| logd | 6.75 | Ph 5; Temp: 25 ° C. | (1) ACD |
| logd | 6.76 | Ph 6; Temp: 25 ° C. | (1) ACD |
| logd | 6.76 | Ph 7; Temp: 25 ° C. | (1) ACD |
| logd | 6.75 | Ph 8; Temp: 25 ° C. | (1) ACD |
| logd | 6.65 | Ph 9; Temp: 25 ° C. | (1) ACD |
| logd | 6.19 | Ph 10; Temp: 25 ° C. | (1) ACD |
| Logp | 6.761 ± 0.669 | Temp: 25 ° C. | (1) ACD |
| Mass intrinsic solubility | 2.0 x 10-4 g/l | Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 0.046 g/l | pH 1; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 5.7 x 10-3 g/l | Ph 2; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 7.6 x 10-4 g/l | Ph 3; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.5 x 10-4 g/l | Ph 4; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.0 x 10-4 g/l | Ph 5; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.0 x 10-4 g/l | Ph 6; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.0 x 10-4 g/l | Ph 7; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.0 x 10-4 g/l | Ph 8; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.5 x 10-4 g/l | Ph 9; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 7.4 x 10-4 g/l | Ph 10; Temp: 25 ° C. | (1) ACD |
| Solubility ng Mass | 2.0 x 10-4 g/l | Hindi nabuong tubig pH 7.00; Temp: 25 ° C. | (1) ACD |
| Molar intrinsic solubility | 2.4 x 10-7 mol/l | Temp: 25 ° C. | (1) ACD |
| Molar solubility | 5.6 x 10-5 mol/l | pH 1; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 7.0 x 10-6 mol/l | Ph 2; Temp: 25 ° C. | (1) ACD |
| Ari -arian | Halaga | Kundisyon | Pinagmulan |
| Molar solubility | 9.3 x 10-7 mol/l | Ph 3; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 3.1 x 10-7 mol/l | Ph 4; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 2.5 x 10-7 mol/l | Ph 5; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 2.4 x 10-7 mol/l | Ph 6; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 2.4 x 10-7 mol/l | Ph 7; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 2.5 x 10-7 mol/l | Ph 8; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 3.1 x 10-7 mol/l | Ph 9; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 9.0 x 10-7 mol/l | Ph 10; Temp: 25 ° C. | (1) ACD |
| Molar solubility | 2.4 x 10-7 mol/l | Hindi nabuong tubig pH 7.00; Temp: 25 ° C. | (1) ACD |
| Molekular na timbang | 818.89 | ||
| PKA | 9.55 ± 0.10 | Karamihan sa acidic temp: 25 ° C. | (1) ACD |
| PKA | 3.45 ± 0.70 | Karamihan sa mga pangunahing temp: 25 ° C. | (1) ACD |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
| Ari -arian | Halaga | Kundisyon | Pinagmulan |
| Malayang rotatable bond | 21 | (1) ACD | |
| H Mga Tanggap | 14 | (1) ACD | |
| H donor | 1 | (1) ACD | |
| H Donor/Acceptor Sum | 15 | (1) ACD | |
| Logp | 6.761 ± 0.669 | Temp: 25 ° C. | (1) ACD |
| Molekular na timbang | 818.89 |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
| Ari -arian | Halaga | Mapagkukunan ng kondisyon |
| Polar Surface Area | 164 A2 | (1) ACD |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software v11.02 (© 1994-2023 ACD/Labs)
Magagamit ang spectra
1 h nmr
13 C NMR
| Pinagmulan ng Hazard Pahayag | |
| H302 nakakapinsala kung nilamon | Pag -uuri at label ng European Chemical Agency (ECHA) Inventory - Nabatid na Pag -uuri at Pag -label - Karamihan sa Mga Karaniwang Abiso, European Chemical Agency (ECHA) Pag -uuri at Pag -label ng Pag -label - Nabatid na Pag -uuri at Pag -label - Karamihan sa Mga Seryosong Abiso |
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