![C43H55N4O10P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methox yethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1- methylethyl)phosphor amidite] (ACI)](http://cdn.globalso.com/nvchem/style/global/img/demo/page_banner.jpg)
![C43H55N4O10P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methox yethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1- methylethyl)phosphor amidite] (ACI) Itinatampok na Larawan](https://cdn.globalso.com/nvchem/C43H55N4O10P-Uridine.png)
C43H55N4O10P Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methox yethyl)- 5-methyl-, 3′ – [2-cyanoethyl N,N-bis(1- methylethyl)phosphor amidite] (ACI)
CAS Registry Number
163878-63-5
H302
| Pangunahing Pisikal na Katangian | Halaga | Kundisyon |
| Molekular na Timbang | 818.89 | - |
| pKa (Hula) | 9.55±0.10 | Pinakamaasim na Temp: 25 °C |
Canonical SMILES
N#CCCOP(OC1C(OC(N2C=C(C(=O))NC2=O)C)C1OCCOC)COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5= CC=C(OC)C=C5)N(C(C)C)C(C)C
Isomeric SMILES
C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](OCCOC)[C@@ H](O1)N2C(=O)NC(=O)C(C)=C2)(C3=CC=C(OC)C=C3)(C4=CC =C(OC)C=C4)C5= CC=CC=C5
InChI
InChI= 1S/C43H55N4O10P/c1-29(2)47(30(3)4)58(55-24-12-23-44)57-38-37(56-41(39(38)53-26- 25-50-6)46-27-31(5)40(48)45-42(46)49)2 8-54-43(32-13-10-9-11-14-32,33-15 -19-35(51-7)20-16-33)34-17-21-36(52-8)22-18-34/h9-11,13-22,27,29-30,37-39 ,41H,12,24-26,28H2, 1-8H3,(H,45,48,49)/t37-,38-,39-,41-,58?/m1/s1
Susi ng InChI
YFRRKZDUDXHJNC-KZQAAKLLSA-N
17 Iba pang Pangalan para sa Substansyang ito
Uridine, 5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ -O-(2-methoxyethyl)- 5-methyl-, 3′ - [2-cyanoethyl bis(1-methylethyl)phosphor
amidite] (9CI); 10: PN: US20030212017 PAGE: 18 inaangkin na RNA; 11: PN: US20030211606 PAGE: 18 inaangkin na RNA; 13: PN: US20040
005569 PAGE: 21 inaangkin na RNA; 13: PN: US20040006030 PAGE: 22 inaangkin na RNA; 13: PN: US20040014048 PAGE: 19 na inaangkin na RNA; 13: PN: US20040014049 PAGE: 19 na inaangkin na RNA; 14: PN: US20030198965 PAGE: 19 na inaangkin na RNA; 14: PN: US20040005565 PAGE: 17- 22 inaangkin na RNA; 14: PN: US20040005570 PAGE: 19 na inaangkin na RNA; 14: PN: US20040014047 PAGE: 19 na inaangkin na RNA; 14: PN: US20040
014699 PAGE: 19 ang nag-claim ng RNA; 15: PN: US20040014050 PAGE: 19 na inaangkin na RNA; 15: PN: US20040014051 PAGE: 21 inaangkin na RNA; 15:
PN: WO03106645 PAGE: 69 inaangkin na RNA; 16: PN: US20040006029 PAGE: 22 inaangkin na RNA; 87: PN: US20040005707 PAGE: 19 na inaangkin na RNA
Available ang spectra
1 H NMR
13 C NMR
Hetero NMR
Available ang mga property
Biyolohikal
Kemikal
Lipinski
Kaugnay na Istruktura
| Ari-arian | Halaga | Kundisyon | Pinagmulan |
| Salik ng Bioconcentration | 348 | pH 1; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 2810 | pH 2; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 21100 | pH 3; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 63100 | pH 4; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 78800 | pH 5; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 80800 | pH 6; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 80800 | pH 7; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 78800 | pH 8; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 63400 | pH 9; Temp: 25 °C | (1) ACD |
| Salik ng Bioconcentration | 21800 | pH 10; Temp: 25 °C | (1) ACD |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Ari-arian | Halaga | Kundisyon | Pinagmulan |
| Sinabi ni Koc | 487 | pH 1; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 3940 | pH 2; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 29600 | pH 3; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 88400 | pH 4; Temp: 25 °C | (1) ACD |
| Ari-arian | Halaga | Kundisyon | Pinagmulan |
| Sinabi ni Koc | 1.10 x 105 | pH 5; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 1.13 x 105 | pH 6; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 1.13 x 105 | pH 7; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 1.10 x 105 | pH 8; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 88800 | pH 9; Temp: 25 °C | (1) ACD |
| Sinabi ni Koc | 30600 | pH 10; Temp: 25 °C | (1) ACD |
| logD | 4.39 | pH 1; Temp: 25 °C | (1) ACD |
| logD | 5.30 | pH 2; Temp: 25 °C | (1) ACD |
| logD | 6.18 | pH 3; Temp: 25 °C | (1) ACD |
| logD | 6.65 | pH 4; Temp: 25 °C | (1) ACD |
| logD | 6.75 | pH 5; Temp: 25 °C | (1) ACD |
| logD | 6.76 | pH 6; Temp: 25 °C | (1) ACD |
| logD | 6.76 | pH 7; Temp: 25 °C | (1) ACD |
| logD | 6.75 | pH 8; Temp: 25 °C | (1) ACD |
| logD | 6.65 | pH 9; Temp: 25 °C | (1) ACD |
| logD | 6.19 | pH 10; Temp: 25 °C | (1) ACD |
| logP | 6.761±0.669 | Temp: 25 °C | (1) ACD |
| Mass Intrinsic Solubility | 2.0 x 10-4 g/L | Temp: 25 °C | (1) ACD |
| Mass Solubility | 0.046 g/L | pH 1; Temp: 25 °C | (1) ACD |
| Mass Solubility | 5.7 x 10-3 g/L | pH 2; Temp: 25 °C | (1) ACD |
| Mass Solubility | 7.6 x 10-4 g/L | pH 3; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.5 x 10-4 g/L | pH 4; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.0 x 10-4 g/L | pH 5; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.0 x 10-4 g/L | pH 6; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.0 x 10-4 g/L | pH 7; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.0 x 10-4 g/L | pH 8; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.5 x 10-4 g/L | pH 9; Temp: 25 °C | (1) ACD |
| Mass Solubility | 7.4 x 10-4 g/L | pH 10; Temp: 25 °C | (1) ACD |
| Mass Solubility | 2.0 x 10-4 g/L | Unbuffered Water pH 7.00; Temp: 25 °C | (1) ACD |
| Molar Intrinsic Solubility | 2.4 x 10-7 mol/L | Temp: 25 °C | (1) ACD |
| Molar Solubility | 5.6 x 10-5 mol/L | pH 1; Temp: 25 °C | (1) ACD |
| Molar Solubility | 7.0 x 10-6 mol/L | pH 2; Temp: 25 °C | (1) ACD |
| Ari-arian | Halaga | Kundisyon | Pinagmulan |
| Molar Solubility | 9.3 x 10-7 mol/L | pH 3; Temp: 25 °C | (1) ACD |
| Molar Solubility | 3.1 x 10-7 mol/L | pH 4; Temp: 25 °C | (1) ACD |
| Molar Solubility | 2.5 x 10-7 mol/L | pH 5; Temp: 25 °C | (1) ACD |
| Molar Solubility | 2.4 x 10-7 mol/L | pH 6; Temp: 25 °C | (1) ACD |
| Molar Solubility | 2.4 x 10-7 mol/L | pH 7; Temp: 25 °C | (1) ACD |
| Molar Solubility | 2.5 x 10-7 mol/L | pH 8; Temp: 25 °C | (1) ACD |
| Molar Solubility | 3.1 x 10-7 mol/L | pH 9; Temp: 25 °C | (1) ACD |
| Molar Solubility | 9.0 x 10-7 mol/L | pH 10; Temp: 25 °C | (1) ACD |
| Molar Solubility | 2.4 x 10-7 mol/L | Unbuffered Water pH 7.00; Temp: 25 °C | (1) ACD |
| Molekular na Timbang | 818.89 | ||
| pKa | 9.55±0.10 | Pinakamaasim na Temp: 25 °C | (1) ACD |
| pKa | 3.45±0.70 | Karamihan sa Pangunahing Temp: 25 °C | (1) ACD |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Ari-arian | Halaga | Kundisyon | Pinagmulan |
| Mga Malayang Naiikot na Bono | 21 | (1) ACD | |
| H Mga Tatanggap | 14 | (1) ACD | |
| H Mga Donor | 1 | (1) ACD | |
| H Donor/Acceptor Sum | 15 | (1) ACD | |
| logP | 6.761±0.669 | Temp: 25 °C | (1) ACD |
| Molekular na Timbang | 818.89 |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
| Ari-arian | Halaga | Pinagmulan ng Kondisyon |
| Polar Surface Area | 164 A2 | (1) ACD |
(1) Kinakalkula gamit ang Advanced Chemistry Development (ACD/Labs) Software V11.02 (© 1994-2023 ACD/Labs)
Available ang spectra
1 H NMR
13 C NMR
| Pinagmulan ng Pahayag ng Hazard ng Code | |
| H302 Mapanganib kung nalunok | Pag-uuri at Pag-label ng European Chemical Agency (ECHA). Imbentaryo - Notified classification at labeling - pinakakaraniwang notification, European Chemical Agency (ECHA) Imbentaryo ng Pag-uuri at Pag-label - Na-notify na pag-uuri at pag-label - pinakaseryosong mga abiso |
![C44H49N5O7Si Adenosine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′- O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI, ACI)](https://cdn.globalso.com/nvchem/C44H49N5O7Si-Adenosine-300x300.jpg)
![C10H12N2O5 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrah ydro-3-hydroxy-2-(hydroxymethyl)- 7-methyl-, (2R,3 R,3aS,9aR)- (9CI, ACI)](https://cdn.globalso.com/nvchem/C10H12N2O5-6H-Furo-300x300.jpg)
![C21H23N3O5 L-Ornithine, N5-(aminocarbonyl)-N2-[(9H-fluoren-9-ylmethoxy) carbonyl]- (9CI, ACI)](https://cdn.globalso.com/nvchem/C21H23N3O5-L-Ornithine-300x300.jpg)
![C41H41N5O8 Adenosine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′- O-(2-methoxyethyl)- (9CI, ACI)](https://cdn.globalso.com/nvchem/C41H41N5O8-Adenosine-300x300.jpg)
![C47H51FN7O7P Adenosine, N-benzoyl-5′ -O- [bis(4-methoxyphenyl)phenylmethyl]-2′ – deoxy-2′ -fluoro-, 3′ – [2-cyanoethyl N,N-bis(1-methylethyl) phosphor amidite] (ACI)](https://cdn.globalso.com/nvchem/C47H51FN7O7P-Adenosine-300x300.png)
![C33H35N3O8 Cytidine, N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O- methyl- (9CI, ACI)](https://cdn.globalso.com/nvchem/C33H35N3O8-Cytidine-300x300.jpg)